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Proton Therapy is a type of precision radiation treatment that uses heavy particles - protons - to irradiate tumour cells.

 


The proton beams are able to release the doses with extreme precision, saving the surrounding healthy tissue. The therapy requires particle production equipment - the cyclotron - and a beam transport and release system. During therapy, the patient is positioned on the treatment bed inside the gantry, the structure that directs the radiation by rotating 360° around the patient. The Trento Centre is equipped with two treatment rooms for patients and one for experimental use and research, with a fixed beam. The Centre is one of the operating units in the Hospital of Trento and is part of the Department of Oncology. It began its clinical activity in October 2014.

The advantages of proton therapy
Extreme precision in releasing radiation Reduction of collateral effects compared to traditional therapy Lower incidence of secondary radiation-induced tumours Particularly effective
for children
Tumours and illnesses treated
Tumours of the brain and skull base Learn more Brain Tumors Learn more Paediatric tumours Learn more Head and neck tumours Learn more Sarcomas Learn more Gastrointestinal tumours Learn more Tumours in genetic syndromes Learn more Tumours of the spinal column and sacrum Learn more Re-treatment of tumours Learn more
 
Scientific publications
Response to "Letter regarding Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy".
Radiother Oncol. 2024 Jan;190:109961. doi: 10.1016/j.radonc.2023.109961. Epub 2023 Oct 21.
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Proton versus photon therapy for esophageal cancer - A trimodality strategy
Radiother Oncol. 2024 Jan;190:109980. doi: 10.1016/j.radonc.2023.109980. Epub 2023 Nov 5. A multicenter international randomized phase III...
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News and events
Trento strengthens its role as an international hub for FLASH radiotherapy research
Friday, 14 August 2026

For three days, Trento became an international meeting point for scientists working at the forefront of one of the most promising future developments in radiation oncology: FLASH radiotherapy. More than simply hosting the 4th FLASH Workshop – "The Role of Oxygen and Beyond in the FLASH Radiotherapy Mechanism", the city demonstrated how a unique combination of scientific excellence, advanced technology and clinical expertise is creating an ecosystem capable of accelerating the translation of FLASH radiotherapy from laboratory research to future patient care.

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Proton Arc Therapy among the “Top 10 Breakthroughs” of 2025 according to Physics World
Thursday, 26 March 2026

Medical physics and proton therapy in Trento are emerging internationally as leaders in one of the most significant advances in the field of physics applied to oncology. The prestigious journal Physics World has included the first clinical application in Italy of Proton Arc Therapy (PAT) among the Top 10 Breakthroughs of the Year in Physics for 2025 — the list of the ten discoveries or innovations that have contributed most to the development of physics and its applications during the year.

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Provincia autonoma di Trento, in conformità con l'art. 13 della Legge 196/2003 e successive modifiche, dichiara che i dati personali qui raccolti hanno finalità di registrare l'utente, attivare nei suoi confronti il servizio richiesto e fornirgli informazioni sull'attività ed i servizi del Centro di Protonterapia, nonché sulle iniziative e le attività promosse dallo stesso. Tali dati verranno trattati elettronicamente in conformità con le leggi vigenti; si garantisce la riservatezza degli stessi e che non saranno oggetto di comunicazione o diffusione a terzi. L'interessato può esercitare in qualsiasi momento i diritti di cui all'art. 7 della suddetta legge (accesso correzione e cancellazione dei dati), rivolgendosi a Provincia autonoma di Trento, uff.informazioni@provincia.tn.it.
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PROTON THERAPY CENTRE - TRENTO
ADDRESS:
Via Al Desert n.14, 38123 Trento

MAIL:
protonterapia@apss.tn.it

TELEPHONE:
+39 0461 1953100

HOURS: Lun - Ven | 8.30 - 16.00